Sidoo kale loo yaqaan fetuin, thealfa-fetoprotein waa protein si dabiici ah u soo saaray bac jaallo ah iyo beerka du ilmaha caloosha ku xagga horumarka. Waxa laga helaa dhiiga uurjiifka iyo hooyada (inta uurka leh). Dhallaanka cusub, heerkiisu hoos buu u dhacaa dhawr toddobaad ka dib dhalashada.

Dadka qaangaarka ah, alfa-fetoprotein ayaa dib u soo bixi kara inta lagu jiro cudurrada qaarkood, inta badan wakhtiga cagaarshow ama buro.

Falanqaynta Alpha-fetoprotein ayaa laga yaabaa in loo qoro haweeneyda xilliga uurka ama dadka waaweyn ee ka baxsan uurka.

Inta lagu jiro uurka, Falanqaynta alfa-fetoprotein waxa loo isticmaalaa ogaanshaha dhalmada ka hor ee cillado kala duwan waxaana la sameeyaa saddexda bilood ee labaad. Imtixaanku inta badan waa sax inta u dhaxaysa toddobaadyada 16aad iyo 18aad. Falanqaynta alfa-fetoprotein waxay si la mid ah u dhacdaa hormoonnada chorionic gonadotropic hormone (HCG), estriol iyo inhibin A, hormoonnada mandheerta. Hadafka ayaa si gaar ah u ah in la ogaado cilladda tuubada neerfaha (kaas oo noqon doona habdhiska dareenka) ee uurjiifka, sida Spina bifida, laakiin sidoo kale cilladaha koromosoomyada, sida khatarta trisomy 21 (ama Down's syndrome).

Dadka qaangaarka ah (uurka ka baxsan), falanqaynta alfa-fetoprotein ayaa la samayn karaa si loo ogaado dhibaatooyinka beerka ama si loo ogaado kansarrada qaarkood.

Falanqaynta alfa-fetoprotein waxay ka kooban tahay a baaritaanka dhiigga heerka xididka oo uma baahna diyaargarow gaar ah. Dhaqtarku waxa uu dhigayaa goob dalxiis ah cududda hore ee bukaanka, oo qiyaastii 10 sentimitir ka sarraysa goobta uu ka dhacayo xuubka xuubka, badiyaa xaga cirifka suxulka.

Dumarka uurka leh, qayb ka mid ah alfa-fetoprotein uu soo saaro uurjiifku waxay u gudubtaa dhiigga hooyada, sidaas darteed looma baahna muunad amniotic ama uurjiif ah. Muunadda dhiigga waxa loo qaadaa si “caadi ah”.

Dadka qaangaarka ah, ragga iyo dumarka ka baxsan xilliga uurka, qiyaasta caadiga ah ee alfa-fetoprotein waa wax ka yar 10 ng / ml oo dhiig ah.

Kor u kaca heerka alfa-fetoprotein ee dhiiga ayaa muujin kara:

• cudurada beerka, sida cirrhosis, loogu talagalay a kansarka beerka, ka cagaarshowga khamriga ama in cagaarshowga fayras

• un kansarka xiniinyaha, ugxan-sidaha, caloosha, xameetida ama xiidmaha.

Dumarka uurka leh, saddexda bilood ee labaad, heerka alfa-fetoprotein caadi ahaan waa inta u dhaxaysa 10 iyo 200 ng / ml. Heerarka alfa-fetoprotein ee sarreeya waxay keeni kartaa:

• cillad tuubada neerfaha ee uurjiifka soo koraya: Spina bifida, anencephaly

• cillad neerfaha

• hydroencephaly

• cillad ku timaada hunguriga ama kelyaha

Taa beddelkeeda, heerka hoose wuxuu noqon karaa calaamad muujinaysa cillad koromosoomyada sida cilladda Down syndrome-ka (trisomy 21).

Iska jir, si kastaba ha ahaatee, heerka alfa-fetoprotein wuu kala duwan yahay xilliga uurka. Sidaa darteed waxaa muhiim ah in si sax ah loo ogaado heerka uurka ee haweeneydu ku jirto xilliga baaritaanka. Natiijooyinka alfa-fetoprotein aan caadi ahayn waxa kale oo laga yaabaa inay sabab u tahay uur badan ama dhimashada uurjiifka.

Tijaabooyin dheeri ah ayaa sidaas darteed lagama maarmaan u ah haddii ay dhacdo heerar alfa-fetoprotein aan caadi ahayn, sida ultrasound ama amniocentesis (ka saarida dareeraha amniotic ee ku xeeran uurjiifka).