The transaminases waa e gudaha jooga cell, gaar ahaan beerka iyo murqaha. Waxay ku lug leeyihiin falcelin bayooloji ah oo badan.

Waxaa jira laba nooc oo transaminases ah:

• ka AST (aspartate aminotransferases), oo inta badan laga helo beerka, murqaha, wadnaha, kelyaha, maskaxda iyo beeryarada
• ka ALT (alanine aminotransferases), oo xad gaar ah u leh beerka

ASAT-yada waxaa horey loogu qoondeeyay TGO-ga soo gaabinta (ama SGOT ee serum-glutamyl-oxaloacetate-transferase); ALATs hoos yimaada TGP-ga (ama SGPT ee serum-glutamyl-pyruvate-transaminase).

Baaritaanka enzymes-kan waxaa loo isticmaalaa in lagu ogaado dhibaatada beerka: kororkooda dhiigga waxaa sabab u ah sii daynta aan caadiga ahayn ee unugyada beerka ee dhaawacan, tusaale ahaan sababtoo ah cagaarshow, At khamriga ama sunta maandooriyaha, IWM

Sidaas awgeed dhakhtarku waxa laga yaabaa inuu u qoro qiyaas haddii ay dhacdo calaamado guud sida daal, miyir beelid, lallabbo, cagaarshow (cagaarshow) iwm. Waxa kale oo uu ku amri karaa baaritaankan dadka khatarta ugu jira dhibaatooyinka beerka:

• halista cagaarshowga B ama C,
• isticmaalka daroogada xididka,
• cayilka,
• sonkorow
• cudurada difaaca jirka,
• ama qoyska u nugul cudurka beerka.

Qiyaasta waxaa lagu sameeyaa muunad dhiig oo fudud, inta badan waxaa laga qaadaa laabta suxulka. Shuruudo gaar ah loogama baahna muunaddan (laakin baaritaannada kale ee lagu codsado isla warbixinta ayaa laga yaabaa inay u baahdaan inaad soonto, tusaale ahaan).

Go'aaminta labada transaminases ayaa la fulin doonaa isku mar, waxaana la xisaabin doonaa saamiga ASAT / ALAT, maadaama ay siinayso tilmaamo ku saabsan nooca dhaawaca ama cudurka beerka ee ku lug leh.

Haddii ay dhacdo natiijooyin aan caadi ahayn, imtixaan labaad ayaa laga yaabaa in la codsado si loo xaqiijiyo qiyamka.

Marka qiyaasta ASAT iyo gaar ahaan ALT ay si aan caadi ahayn u sarreeyaan, tani badanaa waa calaamad muujinaysa dhaawaca beerka.

Si kastaba ha ahaatee, xanuunada qaarkood, sida cagaarshowga uu keeno methotrexate ama cagaarshow C oo daba-dheeraada, waxaa laga yaabaa inaysan la socon wax koror ah oo ku yimaada heerarka transaminase.

Heerka sare u kaca ee transaminases caadi ahaan waxay siinaysaa dhakhtarka tilmaamo wanaagsan oo ku saabsan cudurka:

• A wax yar kac (in ka yar 2 ilaa 3 jeer heerka caadiga ah) si dhexdhexaad ah (3 ilaa 10 jeer heerka caadiga ah) lagu arko khalkhalka beerka ee la xiriira khamriga, cagaarshowga fayraska ee daba-dheeraada, ama steatosis (ururinta baruurta ee beerka unugyada), tusaale ahaan. Dhanka kale, saamiga ASAT / ALAT> 2 ayaa aad u soo jeedinaya cudurka beerka ee khamriga.
• A sare sare (in ka badan 10 ilaa 20 jeer sida caadiga ah) waxay u dhigantaa cagaarshow fayras oo ba'an (kor u kaca wuxuu noqon karaa mid aad u muhiim ah 4 ilaa 6 asbuuc ka dib faddaraynta), dhaawacyada ay keento daroogooyinka ama sakhradda, iyo sidoo kale " ischemia hepatic (qayb joojinta joojinta dhiiga beerka ku shuba).

Dhakhtarku waxa laga yaabaa inuu dalbado baadhitaano kale ama baadhitaano si loo xaqiijiyo ogaanshaha Daaweynta la bilaabay dabcan waxay ku xirnaan doontaa cudurka laga hadlayo.