Cilmi-baaristu waxay suurtagelisay horumar weyn oo xagga daaweynta calaamadaha du lupus. Si kastaba ha ahaatee, ma jiro daawo rasmi ah oo loogu talagalay cudurkan. Daawooyinku waxay wanaajiyaan tayada nolosha iyagoo hoos u dhigaya xoojinta calaamadaha, yaraynta khatarta dhibaatooyinka iyo kordhinta rajada nolosha.

Sida habboon, daaweynta ee lupus Daawooyin yar oo suurtogal ah iyo wakhtiga ugu gaaban, si loo dejiyo ololka. Dadka qaar uma baahna wax dawo ah, qaar kalena waxay u isticmaalaan oo keliya sidii loo baahnaa ama waqtiyo gaaban (flare-up), laakiin dad badan ayaa u baahan inay qaataan daawaynta muddo dheer.

Daawooyinka daroogada

Daawooyinka xanuunka (daawoyinka nonsteroid anti-inflammatory). Acetaminophen (Tylenol®, Atosol®) iyo dawooyinka ka hortagga bararka²⁵ miiska laga gadan karo (ibuprofen, Advil®, ama Motrin) waxa loo isticmaali karaa in lagu yareeyo xanuunka goysyada, marka lupus uusan aad u darneyn ama ololka uusan aad u darneyn. Si kastaba ha ahaatee, dhakhaatiirtu kuma talinayaan in dadka qaba a lupus ka daran iskood u qaataan dawooyinka xanuunka fududeeya. Daawooyinkani waxay kordhin karaan halista dhibaatooyinka ka yimaada lupus, gaar ahaan dhaawaca kelyaha. Waxa laga yaabaa inay qaadato wakhti in la helo dawada saxda ah ee ka hortagga bararka oo la hagaajiso qiyaasta dhakhtarkaaga.

Corticosteroids. Corticosteroids, gaar ahaan prednisone iyo methylprednisone, ayaa ah daawooyinka ugu waxtarka badan ee ka hortagga bararka ee daaweynta. lupus, marka uu cudurku saameeyo dhowr xubnood. Isticmaalka tan iyo horraantii 1960-meeyadii ka dhanka ah lupus, prednisone (Deltasone®, Orasone®) waxay si dhakhso ah u noqotay dawo lama huraan u ah hagaajinta tayada nolosha bukaanka. Waxay kaa caawinaysaa dhimista bararka iyo xakamaynta calaamadaha, gaar ahaan marka ay kacsan tahay. Si kastaba ha noqotee, corticosteroids oo la qaato qiyaaso badan ama waqti dheer waxay sababi kartaa taxane ahDhibaatooyinka ay keento, oo ay ku jiraan bilawga nabarrada, isbeddellada niyadda, sonkorowga^25-26 Dhibaatooyinka aragga (cataracts), cadaadiska dhiigga oo kordha iyo lafaha daciifka ah (osteoporosis). Qiyaasta si fiican ayaa loo hagaajiyaa dhakhtarka si loo helo waxyeellooyin yar intii suurtagal ah. Muddada gaaban, dhibaatooyinka ugu muhiimsan ee corticosteroids waa korodhka miisaanka iyo bararka wejiga iyo jidhka ( bararka). Isticmaalka kaalshiyamka iyo fitamiin D-ga ayaa kaa caawinaysa dhimista halista lafo-jileecu.

Kareemada iyo daawaynta deegaanka. Finanka ayaa mararka qaarkood lagu daaweeyaa kiriimyo, inta badan waxaa lagu daaweeyaa corticosteroids.

Daawooyinka ka hortagga duumada. Hydroxychloroquine (Plaquenil®) iyo chloroquine (Aralen®) - daawooyinka sidoo kale loo isticmaalo daawaynta duumada - wax ku ool u yihiin daaweynta lupus marka dawooyinka aan isteeroydhiska ka-hortagga bararka ku filnayn. Waxay yareeyaan xanuunka iyo bararka xubnaha waxayna caawiyaan daaweynta finanka. Mid ka mid ah daawooyinkan ayaa la qaadan karaa laga bilaabo guga ilaa dayrta si looga hortago bilawga nabarrada maqaarka. qorraxdu. Hydroxychloroquine sidoo kale waxaa loo isticmaalaa daawaynta aasaasiga ah si looga hortago soo noqoshada. Waxyeellada ugu weyn ee dawooyinkaan waa calool xanuun iyo lallabbo.

Immunosuppressants. Wakiilada difaaca jirka waxay yareeyaan dhaqdhaqaaqa nidaamka difaaca ee ka dhanka ah xubnihiisa iyo unugyadiisa. Daawooyinkan xooggan waxaa loo isticmaalaa qayb yar oo dadka ah marka prednisone aysan ka caawinin calaamadaha ama marka ay keento waxyeelooyin aad u badan. Waxay u baahan yihiin marka lupus waxay saamaysaa shaqada dhexda ama nidaam walwal. Kuwa ugu badan ee la isticmaalo waa cyclophosphamide (Cytoxan®), azathioprine (Imuran®) iyo mycophenolate mofetil (Cellcept®). Bukaanjiifka qaarkood, daawada methotrexate (Folex®, Rheumatrex®) ayaa sidoo kale loo isticmaali karaa qiyaas yar sida daawaynta dayactirka ah. Daawooyinkani waxa kale oo ay leeyihiin qaybtooda waxyeelooyin soo raaca, kuwaas oo ay ugu muhiimsan yihiin u nuglaanta caabuqyada iyo khatarta sare ee in uu ku dhaco kansarka. Daawo cusub, belimumab (Benlysta) ayaa laga yaabaa inay waxtar u yeelato xaaladaha qaarkood ee lupus; waxyeellooyinkeeda suurtagalka ah waa lallabbo, shuban iyo qandho²⁵.

kale

Faleebo Immunoglobulin ah. Immunoglobulin (antibody) diyaarinta waxaa laga helaa dhiiga deeq bixiyayaasha. Xididdada laga maamulo, waxay leeyihiin fal-bararka ka-hortagga, maadaama ay qayb ahaan ka takhalusaan autoantibodies, ie unugyada aan caadiga ahayn ee ka-hortagga jidhka oo ku lug leh lupus. Faleebo Immunoglobulin ah ayaa loo qoondeeyay kiisaska lupus ee u adkaysta daawaynta kale, sida corticosteroids.