Daawooyinka joojiya dhaqdhaqaaqa borotiinka habka difaaca jirka - gamma interferon ayaa xannibaya horumarinta melanoma - kansarka maqaarka ee khatarta ah - sida ay saynisyahano Maraykan ah ku sheegeen joornaalka Nature.
Soo-gaadhista iftiinka ultraviolet iyo shucaaca ayaa ah labada sababood ee ugu waaweyn ee horumarinta melanoma - kansarka maqaarka ee ugu xun. Nasiib darro, ilaa hadda hababka molecular ee horumarinta kansarkan si buuxda looma fahmin.
Glenn Merlino iyo asxaabtiisa Machadka Qaranka ee Kansarka ee Bethesda ayaa daraasad ku sameeyay saamaynta shucaaca UVB ee jiirarka. Saynis yahanadu waxay muujiyeen in UVB ay keento macrophages inay ku qulqulaan maqaarka. Macrophages waa nooc ka mid ah unugyada dhiigga cad, unugyo soo saara interferon gamma, borotiinka kiimikaad tilmaamaya horumarinta melanoma.
Joojinta dhaqdhaqaaqa gamma interferon (ie interferon type II) iyada oo la kaashanayo unugyada difaaca jirka ee ku habboon waxay joojisaa koritaanka aan caadiga ahayn ee unugyada maqaarka iyo horumarinta kansarka, xannibaadda interferon I wax saameyn ah kuma laha.
Nooca I interferon waxaa loo aqoonsan yahay borotiinada ka hortagga kansarka oo mid ka mid ah, interferon alpha, ayaa loo isticmaalaa in lagu daweeyo melanoma. Helitaanka in gamma interferon uu leeyahay saamayn lid ku ah oo kor u qaadaysa horumarinta kansarka waa yaab. Joojinta gamma interferon ama borotiinada ay saamayso waxay u muuqataa inay bartilmaameed fiican u tahay daawaynta melanoma. (PAP)