Saynisyahannadu waxay si isdaba joog ah ula xiriireen cunista hilibka cas ee muddada dheer iyo halista sii kordheysa ee kansarrada qaarkood, gaar ahaan kansarka malawadka.
Hadda cilmi-baarayaasha Jaamacadda California (UC), San Diego, waxay heleen caddeyn muujineysa in hilibka cas uu ku jiro nooc sonkor gaar ah oo gacan ka geysan kara caabuqa iyo horumarka kansarka.
Si kastaba ha noqotee, dhammaan tijaabooyinka waxaa lagu qaaday jiirka, natiijooyinkoodana wali way adagtahay in lagu soo rogo bini-aadamka - saynisyahannada qudhooda ayaa qiraya tan maqaal lagu daabacay ilaha internetka. Dacwadaha of ka Qaranka Akademiyada of Science.
Cilmi baarayaashu waxay diirada saareen sonkorta loo yaqaan "bilaa-aadanka" sialic acid - N-glycolylneuraminic acid (New5Gc), kaas oo si dabiici ah ugu jira noolaha naasleyda badankeeda, laakiin aan ahayn bini -aadamka. Sonkortaan waxaa laga helaa noocyo badan oo hilib ah, gaar ahaan kuwa caan ku ah dadka hilibka cuna-hilibka lo'da, doofaarka, wan.
Baarayaasha waxay soo jeediyeen in cunista hilibka guduudan ay horseedi karto caabuq hadii nidaamka jirka ee bini’aadamka uu had iyo jeer soo saaro unugyada difaaca jirka ee xoolaha la cuno. New5Gc, taasi waa, maaddooyin shisheeye ah.
Si loo tijaabiyo mala-awaalkan, kooxdu waxay u baahan tahay qaab xayawaan ah, oo sida aadanaha oo kale ah, aan soo saari doonin New5Gc.
Waxay ku guuleysteen inay abuuraan moodeelka la doonayo iyada oo loo marayo injineernimada hidda-wadaha: jiirradan ma aysan sameysmin New5Gc iyo, sidaa darteed, unugyada difaaca jirka ayaa laga soo saaray taas, taas oo ku dayanaysa xaalada jidhka bini'aadamka.
Markii jiirarkan la siiyay New5Gc, caabuq nidaamsan ayaa ku soo kordhay jidhkooda, iyo burooyin iskood u bilaabmay inay ka samaysmaan beerka, kaas oo New5Gc… Sida ay cilmi-baarayaashu soo jeediyeen, jiirka noocan oo kale ah wuxuu u nugul yahay muuqaalka burooyinka beerka, kuwaas oo, marka loo eego, sharxaya sababta ay burooyinka halista ahi halkaa uga soo baxeen.
Markii ugu horreysay, waxaan si toos ah u muujinnay, annaga oo u ekeysiinay xaalad la mid ah tan ku dhacda jirka aadanaha, in adeegsiga bani'aadamnimada ka baxsan New5Gc iyo soo saarista unugyada difaaca jirka ee jirka New5Gc waxay kordhisaa halista kansarrada lama filaanka ah ee jiirka ku dhaca, ”ayuu yiri qoraaga hormoodka ah ee daraasadda ku takhasusay Ajit Varki, MD oo ka tirsan xarunta cilmi baarista kansarka ee jaamacadda war saxaafadeed.UC Saint Diego Moore Kansarka Xarunta).
“Illaa iyo hadda, dhammaan caddaymaheenna ku saabsan xiriirka ka dhexeeya kansarka iyo New5Gc waxay ahaayeen shilal ama aan toos ahayn, tan iyo markii la helay iyada oo aan lagu samayn tijaabooyin ku saabsan noolaha, ayuu raaciyay. Aad bay u adkaan doontaa in la helo xaqiijinta ugu dambeysa ee tijaabooyinka aadanaha, ”ayuu yiri A. Varki.
Si kastaba ha noqotee, xogtan cusub waxay gacan ka geysaneysaa sharraxaadda xiriirka ka dhexeyn kara cunista hilibka cas iyo horumarinta cudurrada kale ee ka sii daraya caabuq joogto ah, sida atherosclerosis iyo nooca II diabetes.
Daraasaddan cusub waxay gacan weyn ka geysaneysaa horumarinta fikradaha horey u jiray ee ku saabsan cunista hilibka cas iyo dhacdada kansarka. Markii hore, isku xirnaanta dhacdooyinkan si buuxda looma xaqiijin.
Konsumsi daging merah berlebihan bisa meningkatkan risiko inflamasi usus seperti penyakit Crohn dan kolitis ulseratif.
Konsumsi daging merah yang berlebihan bisa meningkatkan risiko penyakit autoimun seperti sindrom Neu5Gc, penyakit Crohn, kolitis ulseratif, rheumatoid arthritis, penyakit Addison, penyakit lupus dan penyakit Qubuuraha; dan juga bisa menyebabkan penyakit kanker seperti kanker kolorektal.
Konsumsi daging merah yang berlebihan bisa meningkatkan risiko penyakit autoimun seperti sindrom Neu5Gc, penyakit Crohn, kolitis ulseratif, rheumatoid arthritis, penyakit Addison, vitiligo, penyakit lupus, psoriasis, penyakit Graves dan vaskulitis; dan juga bisa meningkatkan risiko penyakit kanker seperti kanker kolorektal.